Bacteria · Species

Klebsiella pneumoniae

Opportunist A gut resident that, when it blooms, can translocate to the liver and drive Th17 inflammation — implicated in IBD and primary sclerosing cholangitis.

Associated with these conditions

Inflammatory bowel disease (IBD) Elevated

Certain gut strains drive Th17 inflammation in models and are enriched in some IBD patients.

Preliminary

Small intestinal bacterial overgrowth (SIBO) Elevated

A common overgrowing organism implicated in some SIBO and its metabolic byproducts.

Preliminary

Primary sclerosing cholangitis Elevated

Gut strains translocate and drive Th17 liver inflammation — a leading mechanistic hypothesis for PSC.

Moderate evidence

Necrotizing enterocolitis Reduced

Reported in Disbiome, HMDAD (1 cited study).

Moderate evidence

Chronic Obstructive Pulmonary Disease Associated with

Reported in Disbiome.

Preliminary

Preeclamsia Associated with

Reported in Disbiome.

Preliminary

Cystic fibrosis Associated with

Reported in Disbiome.

Preliminary

Autism spectrum disorders Associated with

Reported in Disbiome.

Preliminary

Colorectal cancer Associated with

Reported in Disbiome.

Preliminary

periodontitis Associated with

Reported in Disbiome.

Preliminary

Edentulism Associated with

Reported in Disbiome.

Preliminary

Helicobacter pylori infection Associated with

Reported in Disbiome.

Preliminary

Systemic lupus erythematosus Associated with

Reported in Disbiome.

Preliminary

Non-alcoholic fatty liver disease Associated with

Reported in Disbiome.

Preliminary

Obesity Associated with

Reported in Disbiome.

Preliminary

Aerobic vaginitis Associated with

Reported in Disbiome.

Preliminary

Alcoholism Associated with

Reported in Disbiome.

Preliminary

Irritable Bowel Syndrome Associated with

Reported in Peryton.

Preliminary

Colorectal Neoplasms Associated with

Reported in Peryton.

Preliminary

Parkinson Disease Associated with

Reported in Peryton.

Preliminary

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