Bacteria · Species

Bilophila wadsworthia

Opportunist A bile-tolerant, sulfite-reducing bacterium that blooms on high-fat, high-meat diets and can inflame the gut.

Associated with these conditions

Liver cirrhosis Reduced

Reported in HMDAD (1 cited study).

Moderate evidence

Inflammatory bowel disease (IBD) Associated with

Reported in Disbiome, Peryton.

Moderate evidence

Cirrhosis Associated with

Reported in Disbiome.

Preliminary

Obesity Associated with

Reported in Disbiome.

Preliminary

Appendicitis Associated with

Reported in Disbiome.

Preliminary

Colorectal cancer Associated with

Reported in Disbiome.

Preliminary

Colorectal Neoplasms Associated with

Reported in Peryton.

Preliminary

Diarrhea Associated with

Reported in Peryton.

Preliminary

Irritable Bowel Syndrome Associated with

Reported in Peryton.

Preliminary

What shifts it

Dietary fat (type matters) Raises it

Nutrient

Moderate evidence Well-established

Helps make

Hydrogen sulfide (H₂S)neurotransmitter

A gaseous signalling molecule from sulfate-reducing bacteria. At low levels it acts as a neuromodulator and protects the gut; in excess it damages the lining — a genuinely dose-dependent, double-edged signal.

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