Condition

C. difficile infection

3 associated organisms · A case where the microbiome story is causal and actionable: antibiotics collapse diversity, C. difficile overgrows, and restoring the community (faecal transplant) cures most cases.

Symptoms of C. difficile infection can need medical evaluation. Treat these associations as background context only — please see a doctor rather than self-treating.
Organisms associated with C. difficile infection
Clostridioides difficile Pathogen Direct cause of C. difficile infection
Species

Overgrowth of this toxin producer defines the infection, typically after antibiotics clear its competitors.

Well-replicated source: curated sample
Overall diversity Community metric Reduced in C. difficile infection
Community metric

A collapse in diversity removes ‘colonization resistance’ and lets C. difficile take hold; restoring it is curative.

Well-replicated source: curated sample
Enterococcus Opportunist Elevated in C. difficile infection
Genus

Enterococcus expands alongside C. difficile and can worsen disease in models.

Moderate evidence source: curated sample
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